Excellgen/pRB (Retinoblastoma protein)/RP-104/5000 U,Excellgen,,Excellgen,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Excellgen/pRB (Retinoblastoma protein)/RP-104/5000 U

产品编号：RP-104

市场价：¥6760.00

场地：美国(厂家直采)

产品分类：蛋白类>重组蛋白>其它动物抗原>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$338.00

品牌： Excellgen

公司：Excellgen, Inc.

公司分类：

商品介绍

ProductName	pRB(Retinoblastomaprotein)
Size	5000U
Description	RB,theproductofretinoblastomasusceptibilitygeneRB-1,isoneofthebest-studiedtumorsuppressorgeneproducts.AtleasttwootherpRB-relatedproteins,p107andp138,havebeenidentifiedandcharacterized.MutationsinZB-1geneareoftenassociatedwiththeoccurrenceofvarioustumors(1-3).TheactivityofpRBisregulatedthroughphosphorylationinacellcycle-dependentmanner.ThehyperphosphorylatedRBproteinusuallyassociateswiththecellnucleusandbindstranscriptionfactorsoftheE2Ffamily(4,5).pRBrepressestranscriptionofitstargetgenes,suchascdc2,cyclinA,andoncogenec-Myc,c-FosthroughthebindingwithE2Ffactorsandtherebyregulatingcellproliferation(6).
Applications	invitrofunctionstudiesincludingtranscriptionandDNAbindingassays protein-proteininteractionassay cellgrowthandproliferationassays.
Source	Baculovirus-insectcell
FusionTag	6XHis
PurificationMethod	FPLC
UnitDefinition(Activity)	1unitequalsto1nanogramofpurifiedprotein.1unitissufficientforagelmobilityshiftassayina20µlreaction;50unitsaresufficientforreconstitutedtranscriptionassayand100unitsaresufficientforaprotein-proteininteractionassay
Purity	~95%asdeterminedbySDS-PAGE
GeneID	5925
Accession#	NM_000321
GeneName	retinoblastoma1
GeneSymbol	RB-1
GeneSynonyms	RB;pRb;OSRC;pp110;p105-Rb
MW	107.5kDa
ProteinSequence	TPRKTAATAAAAAAEPPAPPPPPPPEEDPEQDSGPEDLPLVRLEFEETEEPDFTALCQKL KIPDHVRERAWLTWEKVSSVDGVLGGYIQKKKELWGICIFIAAVDLDEMSFTFTELQKNI EISVHKFFNLLKEIDTSTKVDNAMSRLLKKYDVLFALFSKLERTCELIYLTQPSSSISTE INSALVLKVSWITFLLAKGEVLQMEDDLVISFQLMLCVLDYFIKLSPPMLLKEPYKTAVI PINGSPRTPRRGQNRSARIAKQLENDTRIIEVLCKEHECNIDEVKNVYFKNFIPFMNSLG LVTSNGLPEVENLSKRYEEIYLKNKDLDARLFLDHDKTLQTDSIDSFETQRTPRKSNLDE EVNVIPPHTPVRTVMNTIQQLMMILNSASDQPSENLISYFNNCTVNPKESILKRVKDIGY IFKEKFAKAVGQGCVEIGSQRYKLGVRLYYRVMESMLKSEEERLSIQNFSKLLNDNIFHM SLLACALEVVMATYSRSTSQNLDSGTDLSFPWILNVLNLKAFDFYKVIESFIKAEGNLTR EMIKHLERCEHRIMESLAWLSDSPLFDLIKQSKDREGPTDHLESACPLNLPLQNNHTAAD MYLSPVRSPKKKGSTTRVNSTANAETQATSAFQTQKPLKSTSLSLFYKKVYRLAYLRLNT LCERLLSEHPELEHIIWTLFQHTLQNEYELMRDRHLDQIMMCSMYGICKVKNIDLKFKII VTAYKDLPHAVQETFKRVLIKEEEYDSIIVFYNSVFMQRLKTNILQYASTRPPTLSPIPH IPRSPYKFPSSPLRIPGGNIYISPLKSPYKISEGLPTPTKMTPRSRILVSIGESFGTSEK FQKINQMVCNSDRVLKRSAEGSNPPKPLKKLRFDIEGSDEADGSKHLPGESKFQQKLAEM TSTRTRMQKQKMNDSMDTSNKEEK
StorageBuffer	20mMTris-Cl(pH8.0),20%Glycerol,100mMKCl,1mMDTTand0.2mMEDTA
Storage	-20to-80°C.
Shipping	4°Cordryice
References	1.Friend,SH.etal.,(1986)Nature323,643-646 2.Lee,WH.etal.,(1987)Science235,1394-1399 3.OnADIm,Z.etal.,(1992)Proc.Natl.Acad.Sci.USA89,6177-6181 4.Chen,PL.etal.,(1989)Cell58,1193-1198 5.Ludlow,JW.etal.,(1989)Cell56,57-65 6.Hinds,PW.etal.,(1992)Cell70,993-1006

品牌介绍

德国Excellgen特色产品包括Cre重组蛋白、ExcellScript 耐热 M-MuLV (MMLV) 逆转录酶、FLP重组蛋白、GeneExpresso™ Max转染试剂。

No.

货号	规格
Excellgen	GeneExpresso™Max Transfection Reagent	2	EG-1089	1ml
Excellgen	Cre Recombinase, TAT-Cre (Tat-NLS-Cre, HTNC, HTNCre)	4	EG-1069	1 mg
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Excellgen	serine/threonine kinase 33, STK33	7	EG-261	100 µg
Excellgen	Alpha-tubulin Rabbit Polyclonal Antibody	9	EG-1000	100 µg
Excellgen	Recombinant Human Interferon alpha-2b, IFN alpha 2b, (rHuIFN-α2b)	11	EG-156	100 µg
Excellgen	Thermus aquaticus Muts DNA mismatch repair protein, 6X His-Taq-Muts	13	EG-266	100 µg
Excellgen	Flag Tag Mouse Monoclonal Antibody (2C5)	15	EG-277	100 µg <span line-height:2;"="" style="outline: none; font-size: 14px; font-family: "Microsoft YaHei"; line-height: 2;">