| ProductName | SV40T-Antigen(SimianVirus40LargeAntigen) |
| Size | 5,000U |
| Description | ThelargeTantigen(TAg)ofSimianvirus40actsasaninitiatorofDNAreplication,participatesincellulartransformation,andinducescellgrowth(1-4).AnumberoffunctionaldomainshavebeencharacterizedincludingtheN-terminalJdomain,nuclearlocalizationsignal(NLS),internalhelicasedomain,RbandtopoisomeraseIinteractingdomain,p53andATPbindingdomain(5,6).Thep53-interactingdomainisalsoessentialforbindingp300/CBP(7).PhosphorylationofTAgbyseveralkinasesmayregulateitsfunctionbothpositivelyandnegatively(8). |
| Applications |
|
| Source | Baculovirus-insectcell |
| FusionTag | 6XHis |
| PurificationMethod | FPLC |
| UnitDefinition(Activity) | 1unitequalsto1nanogramofpurifiedprotein.50-500unitsaresufficientforaninvitrounwindingassayand100unitsaresufficientforaprotein-proteininteractionassay. |
| Purity | ~95%asdeterminedbySDS-PAGE |
| GeneID | 11039991 |
| Accession# | AAG39214.1 |
| GeneName | SV-12_gp5largeTantigen |
| GeneSymbol | SV-12_gp5 |
| MW | 83.3kDa |
| ProteinSequence | MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYK KMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADS QHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYS VTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDP FSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFE MCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQM LTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKR YWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGG ESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEYSVPKTLQAR FVKQIDFRPKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWK ERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHE TGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET |
| StorageBuffer | 20mMTris-HClpH7.9,100mMNaCl,0.2mMEDTA,1mMDTTand20%glycerol |
| Storage | -20to-80°C. |
| Shipping | 4°Cordryice |
| References | 1.FanningE.,(1992)J.Viol.66,1289-1293. 2.PanZQ.etal.,(1996)J.Biol.Chem.271,22111-22116. 3.Chao,HA.etal.,(2000)Mol.Cell.Biol.20,7624-7633. 4.Quartin,RS.etal.,(1994)J.Viol.68,1334-1341. 5.Marton,A.etal.,(1993)NucleicAcidsRes.21,1689-1695. 6.Kim,HY.etal.,(2001)EMBOJ.20,295-304. 7.Lill,NL.etal.,(1997)Nature387,823-827. 8.Moarefi,IF.etal.,(1993)J.Viol.67,4992-5002. |
德国Excellgen特色产品包括Cre重组蛋白、ExcellScript 耐热 M-MuLV (MMLV) 逆转录酶、FLP重组蛋白、GeneExpresso™ Max转染试剂。
No.
货号 | 规格 | |||
Excellgen | GeneExpresso™Max Transfection Reagent | 2 | EG-1089 | 1ml |
Excellgen | Cre Recombinase, TAT-Cre (Tat-NLS-Cre, HTNC, HTNCre) | 4 | EG-1069 | 1 mg |
Excellgen | Human Protein Kinase Alpha, PKA, C alpha, cAMP-dependent protein 1 mg | |||
Excellgen | serine/threonine kinase 33, STK33 | 7 | EG-261 | 100 µg |
Excellgen | Alpha-tubulin Rabbit Polyclonal Antibody | 9 | EG-1000 | 100 µg |
Excellgen | Recombinant Human Interferon alpha-2b, IFN alpha 2b, (rHuIFN-α2b) | 11 | EG-156 | 100 µg |
Excellgen | Thermus aquaticus Muts DNA mismatch repair protein, 6X His-Taq-Muts | 13 | EG-266 | 100 µg |
Excellgen | Flag Tag Mouse Monoclonal Antibody (2C5) | 15 | EG-277 | 100 µg <span line-height:2;"="" style="outline: none; font-size: 14px; font-family: "Microsoft YaHei"; line-height: 2;"> |
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