Excellgen/Pseudouridine Modified 5 Anti-Reverse Cap Analog (ARCA) capped FLP recombinase mRNA, NLS-hFLP/EG-1044/10 μg,Excellgen,,Excellgen,+,,Array.Array.Array蚂蚁淘厂家直采.

产品名称：Excellgen/Pseudouridine Modified 5 Anti-Reverse Cap Analog (ARCA) capped FLP recombinase mRNA, NLS-hFLP/EG-1044/10 μg

产品编号：EG-1044

市场价：¥7900.00

场地：美国(厂家直采)

产品分类：分子类>克隆和表达>转录表达>

联系QQ：1570468124

电话号码：4000-520-616

邮箱： info@ebiomall.com

美元价：$395.00

品牌： Excellgen

公司：Excellgen, Inc.

公司分类：

商品介绍

Description	FLPrecombinasecatalyzesthesite-specificrecombinationofDNAbetweenFRTsites.Ithasbeenwidelyusedforgeneratingconditionalknockoutmice,mediatedbyFLP/FRTsystem. CodonoptimizedhFLPisahuman-codonoptimizedThermo-stablemutantformofFLP,withenhancedrecombinaseactivitybya4-10foldhigherthanFLPat37°C. RecentstudiesdemonstatedthatpseudouridinemodifiedmRNAsignaficantlyreducePKRactivationincells,therebyenhancestranslationoftheencodedproteinafterbeingdeliveredintoculturecellsorinjectedintoanimals. Pseudouridinemodified5'Anti-ReverseCapAnalog(ARCA)cappedNLS-hFLPrecombinase(humancodon-optimizedNLS-hFLP)mRNAhasbeentestedforFRTrecombinationinFRT-RFP-Stop-FRT-GFPreportercells(e.g.,HEK293,Hela,andNIH3T3),andprimarycells.
Applications	exvivoFRTrecombination. invivoFRTrecombination.
Size	5µg
TransfectionProtocols	1.InvitrogenRNAiMAXmRNATransfectionProtocol 2.MirusBioTransIT-mRNAmRNATransfectionProtocol
Storage	-20°Cor-80°C
Shipping	dryice
References	Kariko,K.etal.IncorporationofpseudouridineintomRNAyieldssuperiornonimmunogenicvectorwithincreasedtranslationalcapacityandBIOLOGicalstABIlity.Mol.Ther.16,1833–1840(2008). Kariko,K.,Muramatsu,H.,Keller,J.M.&Weissman,D.Increasederythropoiesisinmiceinjectedwithsubmicrogramquantitiesofpseudouridine-containingmRNAencodingerythropoietin.Mol.Ther.20,948–953(2012). Kormann,M.S.etal.ExpressionoftherapeuticproteinsafterdeliveryofchemicallymodifiedmRNAinmice.Nat.Biotechnol.29,154–157(2011). Warren,L.etal.HighlyefficientreprogrammingtopluripotencyanddirecteddifferentiationofhumancellswithsyntheticmodifiedmRNA.CellStemCell7,618–630(2010).

品牌介绍

德国Excellgen特色产品包括Cre重组蛋白、ExcellScript 耐热 M-MuLV (MMLV) 逆转录酶、FLP重组蛋白、GeneExpresso™ Max转染试剂。

No.

货号	规格
Excellgen	GeneExpresso™Max Transfection Reagent	2	EG-1089	1ml
Excellgen	Cre Recombinase, TAT-Cre (Tat-NLS-Cre, HTNC, HTNCre)	4	EG-1069	1 mg
Excellgen	Human Protein Kinase Alpha, PKA, C alpha, cAMP-dependent protein 1 mg
Excellgen	serine/threonine kinase 33, STK33	7	EG-261	100 µg
Excellgen	Alpha-tubulin Rabbit Polyclonal Antibody	9	EG-1000	100 µg
Excellgen	Recombinant Human Interferon alpha-2b, IFN alpha 2b, (rHuIFN-α2b)	11	EG-156	100 µg
Excellgen	Thermus aquaticus Muts DNA mismatch repair protein, 6X His-Taq-Muts	13	EG-266	100 µg
Excellgen	Flag Tag Mouse Monoclonal Antibody (2C5)	15	EG-277	100 µg <span line-height:2;"="" style="outline: none; font-size: 14px; font-family: "Microsoft YaHei"; line-height: 2;">